Arde’s Laboratories offer tailor-made services for your wide range of requirements. We would like to collaborate with all diverse clients from a Biotech firm or a global pharmaceutical company or an academic university. We work on diversified segments like
- Discovery
- Development of Technologies
- Manufacturing
Discovery
Arde’s Laboratories is a trusted partner for innovator biotech and pharma companies to accelerate their drug discovery journey globally to India using creative chemistry supported by high quality cGMP scale-up services.
We are responsive, flexible and cost-effective in delivering solutions to suit the program requirements of the clients. We built a strong relationship with clients spanning diverse therapeutic areas. Our strong and growing scientific team provides a fully- integrated services.
Drug Discovery Services
Arde’s Laboratories delivers integrated discovery services spanning synthetic and medicinal chemistry to a global client base across diverse therapeutic areas. We will reduce the time to clinic for your drug candidate.
Synthetic & Medicinal Chemistry
Specialized in the synthesis of complex chemical entities and peptides to advance your drug discovery programs.
Our team of synthetic and medicinal chemists have consistently work to deliver high quality and value-added services to support the diverse synthetic (chemical & peptide) and drug discovery needs of innovator big pharma companies globally.
Our key services:
- Design and synthesis of analogues to support lead generation and optimization
- Design and synthesis of key intermediates
- Preparation of building blocks of peptides and oligonucleotides.
- Synthesis of reference compounds, metabolites and critical impurities.
Development of Technologies
Arde’s Laboratories had a strong team of scientists and process engineers. We can be able to take any challenge on developing a complex chemical synthesis process from route scouting, process development, scale-up to pilot and commercial scales.
Route Scouting
Designing an innovative route of synthesis (ROS)
We develop alternate Routes of Synthesis (ROS) along the journey from brainstorming to conducting a techno-commercial evaluation, establishing a proof-of-concept, and finally ensuring sustainability of the process.
We had an extremely skilled manpower which can develop highly robust, cost effective processes which can be easily scalable and commercialized.
The IP clearance for all our processes are verified by highly experienced industrial veterans.
We had strong regulatory team with a lot of experience in filling of the projects to all countries.
Analytical method development & validation
Experienced team, well-versed with relevant global guidelines and customer expectations.
- Appropriate use of complementing analytical techniques
- Common method approach for building efficiency within the analytical method
- Development and validation of stability indicating methods
- Comprehensive and readymade stability reports for regulatory submission
- cGMP registration stability programs
- Surrogate method to confirm the quality of large molecules like peptides and oligonucleotides for same technique.
Analysis of specialized Key Raw materials used in the synthesis of large molecules,
- Nucleosides
- Amidites
- Carbohydrates
- Natural Products
- Peptides and several non-chromophoric compounds
- Highly hygroscopic as well as volatile compounds
Technology Transfer
Arde’s technology transfer services ensure smooth scale-up of chemical processes.
Arde’s team of process engineers work along with the process development chemists to prepare robust processes for scale-up. Full-fledged process safety evaluations ensure that the operators are not put at risk and the product can be produced in-spec.
- Team of process engineers closely working with the chemists during development to evaluate each step of process and take it for scale up stepwise.
- Tech absorption engineers at the site will take up the tasks to understand the process needs and retrofit plant in parallel stage wise manner.
- Full-fledged process safety evaluation will be taken care.
- Scale-up facility at the R&D centre to mimic plant conditions.
- Detailed checklists and SOP for tech transfer.
Manufacturing
Arde’s Laboratories works on manufacturing of small molecules, peptides. We make high quality APIs and intermediates that serve them to highly regulated markets globally (USA, Europe, Japan, Australia). The manufacturing facilities we tide up as third part are equipped with flexible and versatile infrastructure, tailored to fit the smaller volume as well as larger volumes with more complex chemistries. We are investing in making our own facility where we can cater the needs of clients within a single site.
